The underlying mechanism which all LSD have in common is the dysfunction, deficiency or complete absence of an enzyme in the cells of the body.
The enzymes affected by LSDs are porting which breakdown waste products in cells. In each cell they are found in in sac-like bodies called lysosomes. The lysosomes and the enzymes they contain act as the 'waste disposal' or 'recycling' unit of each cell. While we don't really generally pay any attention to them, they go about keeping our cells functioning properly in all parts of the body.
In a normal healthy functioning cell, each lysosome, depending on the enzyme it contains, is programmed to attach to a specific substance. They fuse/engulf the target substance (waste) and the enzymes within the lysosome then break the waste/substance into basic molecules. These molecules are then either removed from the cell or recycles as 'spare parts' to form other needed substances.
In individuals with a LSD, the enzyme responsible for breaking down a particular substance is either faulty it absent. This means that a specific waste product has no way of being disposed of. The lysosomes within the cell fuse/engulf the waste material, but instead of breaking to down. it starts to expand and grow with increasing amounts of unbroken waste. they lysosomes packed with waste material enlarge until they fill the whole cell - interrupting its normal function.
All the symptoms that result from a particular LSD are related to the accumulation of waste within certain cells. There are literally hundreds and thousands of enzymes going about their work in our body.
Depending on the enzyme which is missing or malfunctioning, the particular waste product it was meant to recycle will accumulate. Some of these waste products are naturally found in higher quantities in different parts of the body. This explains why different LSDs cause different symptoms.
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